对子宫内膜异位症的有治疗潜力的中医方剂

  • 来源:上海南浦妇科医院
  • 时间:07-06 14:58:42

  由于本文是翻译文,所以在上有一定的难度,*先对子宫内膜异位症要有一定的了解,请阅读:什么是子宫内膜异位症。
 
  这是一种传统中医方剂,它的名字叫温肾消症汤,不过在了解中医方剂作用之前,先对子宫内膜异位症作一个概况。
 
  子宫内膜异位症是以盆腔疼痛和不孕为特点的妇科常见病、多发病。该病具有病程长,缠绵难愈,呈持续性病变的特点,严重影响女性身心健康。
 
  中医学对子宫内膜异位症病机分析主要体现在血瘀证方面,通常从肾虚血瘀论治。中西医结合治疗本病的作用机理可能是通过抑制异位内膜生长、改善血管内环境及调节免疫功能等作用而缩小病灶范围,以改善临床症状、体征,具有不影响卵巢功能、副反应小、不易反弹等优势,这些方面均优于单纯西医治疗。
 
  本研究的目的是通过中医方剂来做实验,那么温肾消症汤到底对子宫内膜异位症有没有*果呢?科学家用白鼠做了实验。发现,4个星期过后,此实验的*果非常好,温肾消症汤可以通过抑制炎性细胞因子的生产和调节子宫内膜异位病灶的侵袭相关基因来抑制子宫内膜异位症的发病。
 
  此实验的过程这里不细讲。上海南浦妇科医院通过此技术发明了温肾消症汤治疗原理,现在能对子宫内膜异位症把握。通过这个技术,我院成功了所有来我院治疗子宫内膜异位症的患者。如果您想对温肾消症汤有一个*面的了解,您可以咨询在线专家。如果您患有子宫内膜异位症,请来院治疗。
 
  由于过实验过程是英文,且对于阅读者没有实用性,所以没有翻译,以下是实验原文:
 
  Abstract
 
  The objective of this study is to investigate the effect of Wenshen Xiaozheng Tang (WXT) on the development of endometriosis in a rat model. Sprague-Dawley rats in which endometriotic implants were induced were divided randomly into 3 groups. The rats in the low-dose and high-dose WXT groups were administered WXT 8.57 and 17.14 g/kg/d, respectively. The rats in the control groups received an equal volume of dissolvent, as did the sham-operated rats. After treatment for 4 weeks, WXT significantly decreased the mean lesion size as well as the peritoneal fluid and serum levels of tumor necrosis factor α and interleukin 1β. Cyclooxygenase-2, matrix metalloproteinase 9, plasminogen activator inhibitor 1, and intercellular adhesion molecule 1 messenger RNA (mRNA) levels were downregulated, and the mRNA expression of tissue inhibitor of metalloproteinase 1 was upregulated in the endometriotic lesions of WXT versus control group. Our data suggested that WXT may suppress the development of endometriosis by inhibiting the production of proinflammatory cytokines and regulating the expression of invasion-related genes in the endometriotic lesions.